Distance Education – PG Admission Notification 2026-27
EXPERTISE INFORMATION
Research Group
Areas of Interest
Multidrug resistance mechanism and therapeutic strategies against S. aureus
Dr. Santosh Kumar Sahu
Associate professor, Biotechnology
Ph.D., Biotechnology, M. Sc., Zoology
drsantoshnou@gmail.com
9178939281
20
Publication
Publication
3
Sponsored Projects
Sponsored Projects
Doctoral Students
6
Courses Taught
Courses Taught
PERSONAL INFORMATION
| Course | Year | University |
|---|---|---|
| Ph.D., Biotechnology | 2010 | Department of Biotechnology, Indian Institute of Technology, Madras (IIT Madras) |
| M. Sc., Zoology | 2004 | Department of Zoology, Utkal University, Bhubaneswar |
| B.Sc., (Zoology, Chemistry, Botany) (Zoology Hons) | 2002 | Department of Zoology, Dhenkanal College, Utkal University |
| 10+2 | 1999 | Council of Higher Secondary Education, Odisha |
| 10th | 1997 | Board of Secondary Education, Odisha |
| Position | Institute | Duration |
|---|---|---|
| Associate professor | Dept of Biotechnology, MSCBU | August 2024 to present |
| Assistant professor | Dept of Biotechnology, MSCBU | July 2012-Aug-2023 |
| Research Associate (DST-PURSE) | P.G. Department of Zoology, Utkal University, Vanivihar, Bhubaneswar | 31/03/2012 to 04/07/2012 |
| DBT-Research Associate | Center for Cellular and Molecular Biology, Hyderabad, India | (03/01/2011 to 03/01/2012 |
| Postdoctoral fellow | Weill Cornell Medical College, Cornell University, New York, USA | 15/03/2010 to 31/12/2010 |
| Title | Funding Agency | Amount | Duration | Completed / Ongoing |
|---|---|---|---|---|
| Purification and Characterization of mercuric reductase (Mer A) from highly mercury resistant, biofilm forming bacterial strains isolated from mercury-enriched industrial wastes of Odisha | DST, Govt. of Odisha | 8.51 Lakhs | 3 years | Completed |
| Synthesis of Novel Therapeutic Phyto-conjugates against Multi-drug Resistant S. aureus from flippase inducing Phytochemicals of Gymnema sylvestre and natural anti-S. aureus prodrugs” | DST, Govt. of Odisha | 9.96 Lakh | 3 years | Ongoing |
| Purification and characterization of the resistance factor from Nyctanthes arbortristis that stimulates membrane lipid modification-induced drug resistance in S. aureus | DST, Govt. of India | 30 Lakh | 3years | Ongoing |
| Paper Code | Paper Name | Teaching Years |
|---|---|---|
| BT102 | Biochemistry | 2012-2026 |
| BT202 | Enzymology | 2012-2026 |
| BT301 | Genetic Engineering | 2012-2026 |
| BT206 (OE) | Rdna Technology | 2020-2026 |
| BT402 | Bioethics, Biosafety And Bio-enterpreneurship Development | 2020-2026 |
| Certificate Course | Clinical Biochemistry And Molecular Diagnostics | 2022-2026 |
| Type: M.Phil. / Ph.D. | Title | Enrolled Year | Graduated Year | Role: Supervisor /Co-Supervisor |
|---|---|---|---|---|
| Jesus Ray R.N. :13001N15008 | Biochemical studies on phospholipase activity of total venom from eastern Indian viper (Daboia russelli) | 2015 | 05/05/2016 | Co-Supervisor |
| Susmita Pati R.N.:M16101N15003 | Screening of Anticancer activity potential of Selected Medicinal Plants of Odisha and Evaluation of their Cytotoxic Potential on Malignant Cells | 2015 | 26/09/2016 | Supervisor |
| Sibani Pal R.N.:M16101N16003 | Production of industrially important enzymes from mercury tolerant soil bacteria | 2016 | 01/09/2017 | Supervisor |
| Rashmi Shee R.N: M16101N170010 | Evaluation of the antimicrobial potential of Nyctanthes arbor-tristis and Gymnema sylvestre against heavy metal and membrane mediated drug resistance in bacteria | 2017 | 31/08/2019 | Supervisor |
| Upasana Sahoo, R.N: M16101N18009 | Characterization of phospholipase activity in a Hg2+-tolerant Klebsiella pneumonaie | 2018 | 16/08/2019 | Supervisor |
| Swastisarita Shaw, M16101N19006 | Studies on Flippase-mediated drug resistance in “Staphylococcus aureus” | 2019 | 17/03/2021 | Supervisor |
| Swagatika Dehury M16101N20002 | Characterization of antibiotic resistance mechanism in “Staphylococcus aureus” strain MTCC3160 | 2020 | 26/04/2022 | Supervisor |
| Award Name | Awarding Institute | Award Year |
|---|---|---|
| Joint CSIR-UGC Junior Research Fellowship (JRF) and Eligibility for Lectureship-National Eligibility Test (NET) , December 2003 and June 2004. | CSIR, INDIA | 2003 |
| Joint CSIR-UGC Junior Research Fellowship (JRF) and Eligibility for Lectureship-National Eligibility Test (NET), June 2004 | CSIR, INDIA | 2004 |
| Research Associate-ship at Weill Cornell Medical College, NewYork, USA- | WCMC, CORNELL UNIVERSITY, NEWYORK | 2010 |
| JC Bose fellowship at Center for Cellular and Molecular Biology, Hyderabad, India | DBT, INDIA | 2011 |
| DBT-Research Associate-ship, DBT-India, July, 2011 | DBT, INDIA | 2012 |
| Position | From | To |
|---|---|---|
| Life member (Regd No. 326), Proteomics Society of India | 15/03/2016 | to present |
| Life member (No. 230), Zoological Society of Orissa | 30/03/2022 | to present |
Books Chapter Authored (count) : 03
Book Chapter
- S. N. Gummadi, D. S. Kumar, S. S. Dash, S. K. Sahu, Industrially important carbohydrate degrading enzymes from yeasts: pectinases, chitinases and β-1,3-glucanases, Yeast biotechnology: diversity and applications, DOI: 10.1007/978-1-4020-8292-4_30, Springer Netherlands, Dordrecht,, (2009), Chapter 30, Online ISBN: 978-1-4020-8292-4, print ISBN:978-1-4020-8291-7, p. 673-691.,
- H.G. Behuria, N.S. Pal, R.N. Munda and S.K. Sahu, Preparation of giant unilammelar vesicles (GUVs) from bacterial polar lipid extract: Developing a prokaryotic model membrane system, Biotechnology for sustainable utilization of Bioresources, Astral International Pvt. Ltd, New Delhi, 2019, ISBN:978-93-88982-00-9 (HB), Chapter 28, pp 309-320
- S. K. Sahu and H. G. Behuria, Heavy Metal Toxicity and Their Bioremediation Using Microbes, Plants, and Nanobiomaterials, Bioresource Utilization and Management: Applications in therapeutics, Biofuels, Agriculture and Environmental Science, ISBN: 9781771889339, Apple Academic Press, InC, Canada, Chapter 20, pp 457-470, 2021, DOI: 10.1201/9781003057826-24
JOURNAL
- S. K. Sahu, S. N. Gummadi, N. Manoj, G. K. Aradhyam, Scramblases: an overview, Archives of Biochemistry and Biophysics 462 (2007) 103-114. (2022), ISSN: 0003-9861
- S. K. Sahu, S. N. Gummadi, A. Gopalakrishna, Over-expression of recombinant human phospholipid scramblase 1 in E. coli and its purification from inclusion bodies, Biotechnology Letters 37 (2008) 2131-2137. (3106), IF: 2.154, ISSN: 0141-5492
- S. K. Sahu and S. N. Gummadi, Flippase activity in proteoliposomes reconstituted with Spinacea oleracea endoplasmic reticulum membrane proteins: evidence for biogenic membrane flippase in plants, Biochemistry 47 (2008) 10481-10490. (2884), ISSN: 0006-2960, IF: 2.952
- S. K. Sahu, S. N. Gummadi, A. Gopalakrishna, Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell, Biochemica et Biophysica Acta 1790 (2009) 1274-128. (2741), IF: 3.67, ISSN: 0304-4165
- S. K. Sahu, A. Rajasekharan, S. N. Gummadi, GroES and GroEL are essential chaperones for folding of recombinant human phospholipid scramblase1 in E. coli, Biotechnology Letters 31 (2009) 1745-52. (3106), IF: 2.154, ISSN: 0141-5492
- B. Sahoo, S. K. Sahu, T. Swarnkar, Prediction of sub-cellular localization of scramblase protein family, International Journal of Computer & Communication Technology (2010) 79-87, ISSN: 0975-7449
- S. K. Sahu, R. Saxena, A. Chattopadhyay, Cholesterol depletion modulates detergent resistant fraction in plasma membrane leading to reduction of serotonin1A receptor, Molecular Membrane Biology 29 (2012) 290-298. (17890), IF: 1.647, ISSN: 0968-7688
- S. K. Sahu, H. G. Behuria, S. Gupta, B. Sahoo, Sequence analysis of plasma membrane proteins containing CXXC motif, International Journal of Knowledge Discovery in Bioinformatics 5 (2015) 1-15. (10995), ISSN: 1947-9115
- D. Nandi, S. R. Mishra, C. K. Sahu, S. K. Sahu, Ground water quality in industrial belts of Balasore, International Journal of Earth and Atmospheric Sciences (2015) 2, 16-19, ISSN: 2349-9222
- S. K. Sahu et al., Biochemical characterization of high mercury tolerance in Pseudomonas spp., American Journal of Current Microbiology 4 (2016) 41-54, ISSN: 2572-5815
- S. K. Sahu et al., Cobalt-induced cytotoxicity in E. coli mediated by phospholipid modulation, Journal of Advanced Microbiology 5 (2016) 215-223, ISSN: 2349-7785
- H. G. Behuria et al., Evaluation of mercury tolerant Klebsiella pneumoniae, Journal of Applied Microbiology and Biochemistry 2 (2018) 1-7, ISSN: 2576-1412
- S. K. Sahu, H. G. Behuria, H2O2-induced oxidative stress in E. coli, Journal of Applied Microbiology and Biochemistry 2 (2018) 3:10, ISSN: 2576-1412
- S. K. Sahu et al., Copper and iron overload protect E. coli from H2O2, Environmental Sustainability 2 (2019) 23-32, ISSN: 2523-8922
- H. G. Behuria, B. K. Biswal, S. K. Sahu (2020), Electroformation of liposomes, Journal of Liposome Research, DOI: 10.1080/08982104.2020.1800729, IF: 2.9
- H. G. Behuria, S. K. Sahu, Antimicrobial terpenoid fraction from Gymnema sylvestre, Applied Biochemistry and Biotechnology (2020), IF: 2.3
- U. K. Panigrahi et al., ZnO nanoparticles bioactivity, Nano Express 2 (2021) 010012
- H. G. Behuria et al., Antimicrobial phytochemicals and membrane permeability, ACS Omega (2021), IF: 3.7
- H. G. Behuria et al., Phospholipid scramblases in cancer, Frontiers in Genetics (2022), IF: 4.6
- S. Gupta et al., Purification of alkaline phosphatase, Protein Expression and Purification (2023), IF: 1.7
- G. Panda et al., Bacterial membrane role in phytotherapeutics, MDPI Membranes (2022), IF: 4.56
- A. Khatua et al., Cerium-doped MgO nanoparticles antimicrobial study, Journal of Functional Biomaterials (2023), IF: 4.9
- A. Kumar et al., Carbon dots for antibacterial activity, Colloids and Surfaces A (2023)
- T. Mohanta et al., N,S-doped carbon dots for detection, Analyst (2023)
- G. Panda et al., Lipid flip-flop in MRSA, Archives of Biochemistry and Biophysics (2025)
- S.K. Sahu, Science, society and evolution of scientific attitude in human, Alumni Meet-2017, DOI: 10.28921/nrme.sc.1.2017.120, New Madras Education, Pvt., Ltd., ISBN: 978-81-934044-6-1, pp: 11-16
- S. K. Sahu, Scientiic attitude of ignited minds, Alumni meet 2025, Dept. of Biotechnology, MSCBU, Newredmars Education, ISBN: 978-93-63620-xxx, pp: 11-14, DOI: http://doi.org/:10.28921/nrme.book.AM2025.1.247
- H. G. Behuria, G. Panda and S. K. Sahu, Evaluation of Antimicrobial Potential of Nyctanthes arbor-tristis Leaf Extracts, Biodiversity Conservation and Livelihood Management, ISBN 978-93-90435-13-5, Daya Publishing House® A Division of Astral International Pvt. Ltd., New Delhi – 110 002, 2021, Chapter 20, pp: 245-253
- H. G. Behuria, G. Panda and S. K. Sahu, Electroformation of giant unilamellar vesicles from bacterial polar lipid extract using copper electrode, Green Technology for Environment Management, Daya Publishing House®, Astral International Pvt Ltd, NewDelhi-110002, ISBN:978-93-5461-379-1, chapter 15, pp 185-191
- Panda, G., sahu,S.K., Natural Product Mediated Therapeutic Application of Artificial Membrane Models: An Insight, Communities, Biodiversity and Conservation of Similipal, 2025, Daya Publishing House®, A Division of Astral International Pvt. Ltd, New Delhi – 110 002, ISBN: 978-93-5919-453-0, Pages: 189-204